Everything that doesn't violate the laws of physics can (and does) happen in reality
The does part refers to the multiverse.
Arguments that violate the laws of physics are akin to invoking the supernatural and therefore wrong.
Everything that can occur in and influence reality, can be expressed computationally (including thoughts and knowledge creation)
Thinking is a form of computation You have to understand how it works in order to encode it into a program. Induction is therefore wrong.
Knowledge creation is the most significant reality-influencing event
The idea that life and humans are a meaningless cosmic spec of scum is entirely wrong
Not just physical matter, but abstractions can influence reality
Reductionism doesn't suffice to explain why things are happening. They can just give a blank picture of the event